Sublocade and Brixadi: Are They Right for Me?

When it comes to overcoming opioid use disorder (OUD), finding the right treatment option is crucial. The experts at Savida Health understand that every individual’s journey to recovery is unique, and are available to help you explore the options that best suit your needs.

Medication-assisted treatment (MAT) is a common treatment option for opioid addiction, incorporating FDA-approved medications and comprehensive counseling. Two innovative medications used in MAT that have gained attention in recent years are Sublocade and Brixadi. But what are they, and are they the right choice for you? SaVida Health is here to tell you everything there is to know about these two medications.

Key Takeaways:

• Innovative Injectable MAT: Both Sublocade and Brixadi are FDA-approved buprenorphine injections used in Medication-Assisted Treatment (MAT) to eliminate the need for daily oral dosing.
• How They Work: As partial opioid agonists, these medications stabilize brain chemistry to significantly reduce cravings and withdrawal symptoms while blocking the euphoric effects of other opioids.
• Ideal Candidates: These treatments are highly effective for individuals who struggle with daily medication adherence, seek a more discreet treatment profile, or require steady, long-term stability to prevent relapse.
• Side Effect Profile: Common side effects for both include injection site reactions (redness/swelling), headache, nausea, and constipation, which are generally mild and temporary.
• Personalized Care: Choosing between the two depends on your specific recovery goals, lifestyle, and medical history. Consulting with a specialist at SaVida Health is the first step toward a customized plan.

What Are Sublocade and Brixadi?

Sublocade and Brixadi are both FDA-approved medications used to treat moderate to severe opioid use disorder. They belong to a class of drugs called partial opioid agonists, which work by reducing cravings and withdrawal symptoms without producing the euphoric high associated with opioid misuse.

• Sublocade is an extended-release injection of buprenorphine administered monthly by a healthcare provider. It provides a steady dose of medication over time, eliminating the need for daily pills.
• Brixadi is another extended-release buprenorphine injection, but it offers more flexibility in dosing. It’s available in weekly and monthly formulations, allowing for a more personalized treatment approach.
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Both medications are designed to support long-term recovery by providing consistent medication levels, reducing the risk of relapse, and helping individuals focus on their recovery journey.

How Do Sublocade and Brixadi Work?

Sublocade and Brixadi work by binding to the same receptors in the brain that opioids target. However, unlike full opioid agonists (such as heroin or prescription painkillers), they activate these receptors only partially. This means they can:

• Reduce cravings: By stabilizing brain chemistry, these medications help reduce the intense desire to use opioids.
• Prevent withdrawal symptoms: They alleviate the physical discomfort that often accompanies opioid cessation.
• Block the effects of other opioids: If someone tries to use opioids while on Sublocade or Brixadi, the medications can block the euphoric effects, reducing the risk of relapse.

Key Differences: Sublocade vs. Brixadi

Sublocade and Brixadi are both highly effective treatment options for OUD, but there are a few distinctions between the two medications:

• Dosage: Sublocade is offered in two dosage options, 100 or 300 mg. Many patients begin with the heftier dose, but later switch to the latter option when they are further along in their recovery journey. Brixadi, on the other hand, is more flexible, giving you the option to choose between weekly and monthly injections. The weekly dosage options are 8, 16, 24, or 32 mg, while the monthly dosage options are 64, 96, or 128 mg.
• Injection Sites: Brixadi can be injected in the skin of the buttock, thigh, abdomen, or upper arm. The upper arm is the most easily accessible and convenient option, and makes treatment a much more manageable experience. Sublocade can only be injected in the lower abdomen or upper gluteus, which may be less convenient or accessible than Brixadi, but is still an effective treatment option.
• Immediate vs. Extended Release: Brixadi offers an immediate release with its weekly injection option, which can be more effective for managing short-term cravings or withdrawal. Since Sublocade only offers monthly injections, it provides a more extended release, with the medication being slowly delivered into the body over the course of a month.

Who Can Benefit from Sublocade and Brixadi?

Sublocade and Brixadi may be a good fit for individuals who:

1.    Struggle with Daily Medication Adherence

• If taking a daily pill like Suboxone is challenging, these once-monthly or weekly injections can simplify your treatment plan.

2.    Seek Long-Term Stability:

• These medications’ extended-release nature provides consistent support, helping you stay on track with your recovery goals.

3.    Have a History of Relapse

• The steady dosing of Sublocade and Brixadi can help reduce the risk of relapse by minimizing cravings and withdrawal symptoms.

4.    Prefer a Discreet Treatment Option:

• Unlike daily pills, these injections are administered in a clinical setting by care professionals, offering a more private approach to treatment.

Are Sublocade and Brixadi Right for Me?

Deciding whether Sublocade or Brixadi is right for you depends on several factors, including:

• Your Recovery Goals: Are you looking for a long-term solution to manage OUD?
• Your Lifestyle: Would a monthly or weekly injection fit better into your routine than daily medication?
• Your Medical History: Your provider will evaluate your health history to ensure these medications are safe and effective.
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Savida Health experts will work with you to assess your unique situation and create a personalized treatment plan.The SaVida team believes in empowering you with the knowledge and tools you need to make informed decisions about your recovery.

Potential Side Effects

Like all medications, Sublocade and Brixadi may cause side effects. Common side effects include:

• Injection site reactions (redness, itching, or swelling)
• Headache
• Nausea
• Constipation
• Fatigue
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Most side effects are mild and temporary, but discussing any concerns with your healthcare provider is important.

Why Choose Savida Health for Your Recovery Journey?

Savida Health is committed to providing compassionate, evidence-based care for individuals struggling with opioid use disorder. SaVida’s integrated approach combines medication-assisted treatment (MAT) with counseling, behavioral therapy, and support services to address the physical, emotional, and social aspects of recovery.

When you choose Savida Health, you’re not just getting a treatment plan—you’re gaining a partner in your journey to a healthier, more fulfilling life.

SaVida Health has locations across the eastern United States, including within the following states. Find the right treatment facility near you!

• Delaware rehabs & Sublocade / Brixadi clinics
• Maine rehabs & Sublocade / Brixadi clinics
• Massachusetts rehabs & Sublocade / Brixadi clinics
• New Hampshire rehabs & Sublocade / Brixadi clinics
• Vermont rehabs & Sublocade / Brixadi clinics
• Virginia rehabs & Sublocade / Brixadiclinics

Take the First Step Today

If you’re considering Sublocade or Brixadi as part of your recovery plan, we’re here to help. Contact Savida Health today to schedule a consultation and learn more about how these innovative treatments can support your journey to lasting recovery.